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. 2021 Mar 5;2:1–8. doi: 10.1016/j.urine.2021.02.001

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© 2021 The Authors

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 4 — Function distribution of dysregulated proteins in COVID-19 patients. (A&B&C) The volcano plots of the up-regulated and down-regulated proteins in different groups. Proteins with p-Value lower than 0.05 and fold change ≥2 were considered as significantly differential expression. (D) Venn diagrams of differential proteins in mild, severe COVID-19 patients and recovery patients compared with healthy volunteers. (E) The GO analysis of dysregulated proteins in the COVID-19 patients.