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Tear biomarkers in Keratoconus
| Protein | Expression |
|---|---|
| BY ELISA ANALYSIS | |
| IL-6 | Increased |
| TNF-ALPHA | Increased |
| MMP-9 | Increased |
| MMPs-1,3,7,13 | Increased |
| IL-4,5,6,8 | Increased |
| TNF-alpha, beta | Increased |
| SFRP1 | Decreased |
| BY LCMS ANALYSIS (Liquid chromatographytandem Mass spectrometry) | |
| SCGB2A1 | Increased |
| MMP1 | Increased |
| AZGP1 | Decreased |
| LTF | Decreased |
| CYSTATINS | Decreased |
| LCN | Increased |
| AZGP1 | Increased |
| PIP | Increased |
