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. 2021 Feb 15;13(3):e12005. doi: 10.15252/emmm.202012005

Figure 8. Transcriptional changes associated with COCO stimulation in ECs.

Figure 8

  1. Scheme of the protocol to determine differential gene expression after treatment of HUVECs 16 h with COCO.
  2. Differential gene expression heatmap generated by DESeq2 of top‐altered genes of HUVECs treated with COCO compared with PBS‐treated control cells (n = 4 independent samples/group).
  3. GSEA pathway analysis of control vs. COCO‐treated HUVECs for TGFβ, BMP, or ROS pathways.