Skip to main content
. 2021 Jan 20;13(3):e11900. doi: 10.15252/emmm.201911900

Figure EV2. Cardiac function is not significantly affected in CamkIIδc TG mice upon Vorinostat treatment.

Figure EV2

  • A
    Scheme of the experimental design. Vorinostat treat was initiated at 2 month of age and analysis was performed at 3 month of age. n = 12/group.
  • B
    Bar chart showing that body weight was similar among groups. n = 12/group. One‐way ANOVA.
  • C, D
    Bar chart showing that heart weight (C) and left ventricle (LV) weight (D) was increased in vehicle and Vorinostat‐treated CamkIIδc TG mice when compared to the wild‐type vehicle control group. n = 12/group. *P < 0.05, **P < 0.01, ***P < 0.001. Kruskal–Wallis test.
  • E
    Bar charts showing that ejection fraction (left panel), cardiac output (CO; middle panel), and cardiac index (CI, right panel) is significantly impaired in vehicle‐treated CamkIIδc TG mice (n = 12) when compared to corresponding control (n = 12) group. These impairments were not affected by Vorinostat treatment. ****P < 0.0001. ns, not significant, Kruskal–Wallis test.

Data information: Bars and error bars indicate mean ± SEM.