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. 2021 Mar 4;147(5):1–8. doi: 10.1001/jamaoto.2021.0011

Table 1. Demographic, Disease, and Treatment Characteristics of Participants Who Completed the Study.

Characteristic Total Prednisone Placebo Effect size % (95% CI)
Participants, n 72 33 39
Age, mean (SD), y 49.4 (14.9) 48.8 (15.3) 49.9 (14.7) 0.07 (–0.06 to 0.32)
Male sex, No. (%) 36 (50) 18 (54) 18 (46) 8.4 (–14.7 to 31.5)
Race, No. (%)
White non-Hispanic 60 (83) 30 (91) 30 (77) 14.0 (–14.9 to 42.9)
White Hispanic 4 (6) 2 (6) 2 (5) 0.9 (–28.7 to 30.6)
Black 2 (3) 0 2 (5) –5.1 (–35.7 to 25.4)
Asian and Pacific Islander 5 (7) 1 (3) 4 (10) –7.2 (–36.6 to 22.1)
Other 1 (1) 0 1 (3) –2.6 (–33.5 to 28.4)
Comorbidities, No. (%)
Asthma 20 (28) 10 (30) 10 (26) 4.7 (–19.9 to 29.2)
Allergy 16 (22) 5 (15) 11 (3) –13.1 (–38.5 to 12.4)
Depression 9 (13) 7 (21) 2 (5) 16.1 (–11.3 to 43.4)
Smoking 6 (8) 2 (6) 4 (10) –4.2 (–33.1 to 24.7)
Preoperative score, mean, (SD)
SNOT-22 43.4 (21.8) 43.8 (21.5) 43.0 (22.4) 0.04 (–0.02 to 0.35)
Lund-Kennedy endoscopy 3.3 (2.8) 3.8 (3.1) 2.9 (2.5) 0.32 (–0.30 to 0.94)
Lund-Mackay radiograph 6.6 (4.3) 7.1 (4.2) 6.2 (4.4) 0.21 (–0.19 to 0.61)
Surgery characteristic, No. (%)
Revision 38 (52) 21 (64) 17 (44) 20.0 (–2.9 to 42.9)
Unilateral 7 (10) 3 (10) 4 (10) –1.2 (–29.7 to 27.4)
Bilateral 65 (90) 30 (90) 35 (90) 1.2 (–29.8 to 32.1)
Procedure, No. (%)
Maxillary antrostomy 69 (96) 32 (97) 37 (95) 2.1 (–30.7 to 34.8)
Anterior ethmoidectomy 68 (94) 32 (97) 36 (93) 4.7 (–27.6 to 37.0)
Posterior ethmoidectomy 63 (88) 30 (91) 33 (85) 6.3 (–27.6 to 36.4)
Sphenoid sinusotomy 53 (74) 22 (67) 31 (79) –12.8 (–39.0 to 13.3)
Frontal sinusotomy 51 (71) 21 (64) 30 (77) –13.3 (–38.8 to 12.3)
Endoscopic septoplasty 40 (56) 20 (61) 20 (51) 9.3 (–14.1 to 32.8)
Inferior turbinate reduction 42 (58) 17 (52) 25 (64) –12.6 (–36.2 to 11.0)
Concha bullosa resection 17 (23) 7 (21) 10 (26) –4.4 (–29.8 to 20.9)