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. 2021 Feb 19;12:633566. doi: 10.3389/fphar.2021.633566

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Copyright © 2021 Wang, Wu, Zhang, Hu, Liu, Vaziri, Guo, Zhao and Miao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Treatment with PPU and ergone improved aberrant fatty acid metabolism in CRF rats. (A) sPLS-DA of two components of 12 lipid species from control, CRF, CRF + PPU, and CRF + ERG groups. (B) Clustering analysis of 12 lipid species among control, CRF, CRF + PPU, and CRF + ERG groups. (C) Heatmap of 12 lipid species among control, CRF, CRF + PPU, and CRF + ERG groups. Red and green indicate increased and decreased levels, respectively. (D) Relative intensity analysis of 12 lipid species among the control, CRF, CRF + PPU, and CRF + ERG groups. ^# p < 0.05, ^## p < 0.01 compared with control group; ^* p < 0.05, ^** p < 0.01 compared with CRF group.