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. 2021 Feb 26;45(4):45. doi: 10.3892/or.2021.7996

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Copyright: © Qian et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Circ_0000003 facilitates cell invasion and migration capability in TSCC by inhibiting miR-330-3p. (A) Cell invasion levels in TSCC cells after circ_0000003 knockdown. (B) Cell migration levels in TSCC cells after circ_0000003 knockdown. (C) Representative images of the cell migration in Cal27 and SCC1 cells after circ_0000003 knockdown (original magnification, ×200). (D) Cell invasion and (E) migration capability in Cal27 cells transfected with sh-NC, miRNA inhibitor-NC, sh-circ_0000003 + miRNA inhibitor-NC, sh-NC + miR-330-3p inhibitor, and sh-circ_0000003 + miR-330-3p inhibitor. **P<0.01 vs. sh-NC; ^##P<0.01 vs. miRNA inhibitor-NC. (F) Representative images of the cell migration in Cal27 cells after the transfections (original magnification, ×200). circ_0000003, hsa_circ_0000003; TSCC, tongue squamous cell carcinoma; sh-circ_0000003, circ_0000003 shRNA; sh, shRNA; NC, negative control.