Table 1.
Summary of peer reviewed SMC cost and cost-effectiveness estimates
| Setting | Delivery strategy | Unit Cost/US $ (2016)a | Cost–effectiveness ratiosb | |||||
|---|---|---|---|---|---|---|---|---|
| Cost per round | Cost per fully adherent childc | |||||||
| Financial | Economic | Financial | Economic | |||||
|
Hohoe, Ghana (Conteh et al. 2010) |
DTD, 6 rounds, AS + AQ monthly – trial conditions DTD, 6 rounds, AS + AQ monthly – modelled to district level |
1.84 | 2.54 |
13.17 4.02 |
16.70 4.83 |
80.46 (66.18–94.81) per case averted 24.87 (22.63–27.36) per case averted |
||
|
Basse, Gambia (Bojang et al. 2011) |
FPD, 3 rounds, SP + AQ monthly DTD, 3 rounds, SP + AQ monthly |
1.04 0.74 |
1.20 0.97 |
3.31 1.37 |
3.87 1.82 |
Not applicable | ||
|
Jasikan, Ghana (Patoulllard et al. 2012) |
FPD, 3 rounds SP + AQ monthly DTD, 3 rounds, SP + AQ monthly |
2.93–3.09 2.65 |
3.65–3.79 3.46 |
– – |
9.37 8.32 |
Not undertaken | ||
|
Upper West Region, Ghana (Nonvignon et al. 2016) |
DTD, 4 rounds, SP + AQ at monthly | 22.81 |
108.41 (101.01–123.01) per additional case avertedd 3339.97 (3112.03–3789.85) per additional death averted |
|||||
|
Bambey, Mbour, Fatick & Niakhar, Senegal (Pitt et al., 2017) |
DTD, 3 rounds SP + AQ monthly | 0.55 | 0.65 | 1.65 | 1.96 | Not undertaken | ||
| Burkina Faso, Chad, The Gambia, Guinea, Mali, Niger, and Nigeria (ACCESS-SMC Partnership, 2020) |
DTD and FPD (country dependent) 4 rounds SP + AQ monthly |
– | 0.91e | – | – |
2.91–30.73 per case averted 119.63- 506.00 per severe case averted 533.56- 2256.92 per death averted |
||
DTD: Door to Door distribution, FPD: Fixed Point Distribution (Health facility, outreach or focal point in village)
aCosts from Provider perspective and inflated from original source base year to 2016 using Inflation Calculator from U.S. Labor Department's Bureau of Labor Statistics on September 12, 2019
bBased on intervention costs only
cThe unit cost per round weighted by adherence levels
dNonvignon et al. (2016) used a similar approach to this study (combined primary cost data with a transmission model to estimate cost-effectiveness)
eAccording to the manuscript, ‘The weighted average cost of four treatments per child was obtained by dividing the total recurrent cost by the total number of doses administered divided by 4′ (p1834). This amounted to US $3.63, a calculation based on a multiple of treatment rounds that appears to exclude adherence. To obtain the cost per round, US $3.63 was divided by 4. Mali specific costs were not presented