Table 2.

Characteristics of study participants from ROS/MAP (N = 2079) and ADNI1/GO/2 (N = 1419) after QC of genetic data

ROS/MAP	AD (n = 564)	Non-ADa (n = 1515)	Diff (P)b
Sex (F/M)	388 F, 176 M	1060 F, 455 M	0.63
Age at death, years (SD)	90.92 (5.88)	88.10 (6.73)	< 0.0001
APOE ε4 status (−/+)	− 378, + 186 (0.33)	− 1226, + 289 (0.19)	< 0.0001
ADNI	AD (n = 555)	Non-AD (n = 864)	Diff (P)b
Sex (F/M)	231 F, 324 M	372 F, 492 M	0.62
Age at AD, years (SD)	74.78 (8.11)	77.49 (7.33)	< 0.0001
APOE ε4 status (−/+)	−201, + 354 (0.64)	− 568, + 296 (0.34)	< 0.0001

ROS/MAP, The Religious Orders Study/the Rush Memory and Aging Project; ADNI, Alzheimer’s Disease Neuroimaging Initiative; AD, Alzheimer’s disease; Diff, the statistical difference between AD and non-AD; F, female; M, male; SD, standard deviation; Age at AD, age when AD developed for AD patients or age at last valid record for non-AD subjects; APOE ε4 status (−/+), presence of the ε4 allele

^aNon-AD in ROS/MAP includes 713 individuals with missing AD status

^bP values are calculated by Fisher’s exact tests (for sex and APOE ε4 status) or two-sample t tests (for age at death, age at AD)