Table 1.

Correlation between gene expression and methylation of CRC in TCGA database

Gene	Methylation						Expression						Correlation
	Normal			Tumor	P		Normal		Tumor		P		Cor	P
KHDRBS2	0.156 ± 0.031			0.443 ± 0.091	< 0.001		4.678 ± 0.981		0.753 ± 1.007		< 0.001		− 0.594	< 0.001
GPM6A	0.308 ± 0.150			0.325 ± 0.053	< 0.001		7.837 ± 1.658		3.036 ± 2.459		< 0.001		0.018	0.708
HPSE2	0.259 ± 0.022			0.363 ± 0.053	< 0.001		7.536 ± 0.506		3.660 ± 1.555		< 0.001		− 0.351	< 0.001
KCNA1	0.316 ± 0.027			0.557 ± 0.104	0.131		3.389 ± 1.915		1.096 ± 1.367		< 0.001		− 0.383	< 0.001
PHOX2A	0.270 ± 0.038			0.451 ± 0.075	< 0.001		4.470 ± 1.039		1.090 ± 1.259		< 0.001		− 0.411	< 0.001
RSPO2	0.283 ± 0.034			0.450 ± 0.075	< 0.001		7.715 ± 0.906		2.982 ± 1.805		< 0.001		− 0.455	< 0.001
RXRG	0.242 ± 0.137			0.461 ± 0.116	< 0.001		6.019 ± 0.590		1.920 ± 1.284		< 0.001		− 0.404	< 0.001
GFRA1	0.393 ± 0.017			0.571 ± 0.079	< 0.001		9.050 ± 0.826		5.791 ± 1.885		< 0.001		− 0.357	< 0.001
TMEFF2	0.324 ± 0.022			0.517 ± 0.089	< 0.001		5.336 ± 0.848		1.260 ± 1.291		< 0.001		− 0.431	< 0.001
LRRC3B	0.577 ± 0.026			0.534 ± 0.081	0.016		3.120 ± 0.969		0.667 ± 0.874		< 0.001		0.138	0.004
NOVA1	0.175 ± 0.130			0.359 ± 0.118	< 0.001		0.232 ± 0.016		0.437 ± 0.127		< 0.001		− 0.492	< 0.001
ADCYAP1R1	0.431 ± 0.010			0.359 ± 0.059	< 0.001		6.537 ± 1.170		2.442 ± 1.826		< 0.001		0.246	< 0.001
PRIMA1	0.301 ± 0.015			0.390 ± 0.093	< 0.001		9.030 ± 1.064		3.451 ± 2.171		< 0.001		− 0.222	< 0.001
EPHA7	0.121 ± 0.009			0.340 ± 0.155	< 0.001		8.333 ± 1.425		4.669 ± 1.993		< 0.001		− 0.431	< 0.001