Table 2.

Univariate and multivariate analyses of risk factors associated with postoperative complications

Characteristics	Univariate			Multivariate
	OR	95% CI	P	OR	95% CI	P
Age	1.014	1.004–1.025	0.008	1.011	1.000–1.023	0.046
Gender
Male	0.763	0.595–0.977	0.032	0.680	0.525–0.880	0.003
Female
BMI	0.987	0.956–1.020	0.447
Preoperative comorbidities
Previous abdominal surgery	1.003	0.727–1.383	0.988
Diabetes mellitus	1.133	0.768–1.670	0.529
Hypertension	1.136	0.896–1.440	0.291
Preoperative laboratory data
Neutrophil count	1.000	1.000–1.000	0.843
Lymphocyte count	1.000	1.000–1.000	0.054
Platelet count	1.000	1.000–1.000	0.373
Serum albumin	0.555	0.396–0.776	0.001
Total cholesterol	0.995	0.992–0.998	0.004
CRP	1.008	1.000–1.017	0.061
NLR	1.024	0.983–1.068	0.252
PLR	1.002	1.000–1.003	0.018
PNI	0.961	0.939–0.983	0.001
CONUT	1.158	1.081–1.239	< 0.001	1.156	1.077–1.240	< 0.001
ASA ≥ 3	1.039	0.827–1.307	0.740
Mode of surgical approach
Laparoscopic	0.688	0.397–1.195	0.184
Open
Type of resection
Distal gastrectomy	1.204	0.947–1.531	0.129	1.266	0.989–1.621	0.061
Proximal gastrectomy	1.542	1.073–2.215	0.019	1.565	1.081–2.264	0.018
Total gastrectomy
Operation time	1.002	1.000–1.004	0.016	1.003	1.001–1.005	0.003
Blood loss	1.000	1.000–1.001	0.094
Tumor invasion (T3–4)	1.196	0.952–1.504	0.124
pTNM stage (≥ III)	1.039	0.827–1.304	0.743

BMI = body mass index; CRP = C-reactive protein; NLR = neutrophil-to-lymphocyte ratio; PLR = platelet-to-lymphocyte ratio; PNI = Prognostic Nutritional Index; CONUT = Controlling Nutritional Status; ASA = American Society of Anesthesiologists; OR = odds ratio; CI = confidence interval