Table 4.
The performance of each risk factor to predict ipsi-LLNM in patients with PTC
| Parameters | Cutoff value | AUC (95%CI) | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | P Value |
|---|---|---|---|---|---|---|---|
| Tg (ng/mL) | > 100.01 | 0.856 (0.818, 0.889) | 76.56 (68.3, 83.6) | 88.85 (84.5, 92.3) | 76.0 (69.1, 81.7) | 89.2 (85.7, 91.9) | < .0001 |
| Anti-Tg (IU/mL) | > 89.43 | 0.766 (0.721, 0.806) | 71.09 (62.4, 78.8) | 86.33 (81.7, 90.1) | 70.5 (63.6, 76.7) | 86.6 (83.1, 89.5) | < .0001 |
| IC IAP (mg/mL) | > 3.4 | 0.846 (0.807, 0.879) | 72.66 (64.1, 80.2) | 85.97 (81.3, 89.8) | 70.5 (63.6. 76.5) | 87.2 (83.7, 90.1) | < .0001 |
| IC IVP (mg/mL) | > 3.1 | 0.777 (0.733, 0.816) | 53.91 (44.9, 62.8) | 91.37 (87.4, 94.4) | 74.2 (65.5, 81.3) | 81.2 (78.1, 83.9) | < .0001 |
| ETE | N/A | 0.713 (0.667, 0.757) | 66.41 (57.5, 74.5) | 76.26 (70.8, 81.1) | 56.3 (50.2, 62.2) | 83.1 (79.3, 86.4) | < .0001 |
* Data in parentheses are 95% confidence intervals (CIs)
LLNM Lateral cervical lymph node metastasis, PTC Papillary thyroid carcinoma, AUC Area under the curve, PPV Positive predictive value, NPV Negative predictive value, IC Iodine concentration, IAP In the arterial phase, IVP In the venous phase, ETE Extrathyroidal extension