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. 2021 Mar 4;13:38. doi: 10.1186/s13073-021-00849-3

Fig. 2.

Fig. 2

Two-sample Mendelian randomization estimates for the association between genetically predicted systolic blood pressure per 10-mmHg and atrial fibrillation as the main outcome, and coronary heart disease, myocardial infarction, and ischemic stroke as positive control outcomes. Solid squares represent point estimates and vertical lines 95% confidence intervals (CI). Cases and controls: number of cases and controls in genome-wide association studies. Odds ratio estimated using the inverse-variance weighted method