Table 2.
Univariable Cox regression analysis for the risk factors associated with 30-day, 6-month and 1-year mortality
| Variables | 30-day mortality | 1-year mortality | Total mortality | |||
|---|---|---|---|---|---|---|
| HR (95% CI) | p value | HR (95% CI) | p value | HR (95% CI) | p value | |
| Age (per 1 year increase) | 1.12 (1.04–1.21) | 0.002 | 1.07 (1.02–1.12) | 0.008 | 1.08 (1.04–1.12) | < 0.001 |
| Sex (male vs. female) | 4.40 (1.43–16.24) | 0.009 | 3.81 (1.74–8.94) | 0.001 | 2.11 (1.24–3.62) | 0.007 |
| CCI = 0 | 1.00 (Reference) | – | 1.00 (Reference) | – | 1.00 (Reference) | – |
| CCI = 1 | 1.79 (0.33–9.69) | 0.478 | 1.82 (0.62–5.32) | 0.266 | 1.35 (0.67–2.65) | 0.396 |
| CCI ≥ 2 | 9.66 (2.68–44.83) | 0.001 | 7.53 (3.03–20.24) | < 0.001 | 5.03 (2.69–9.42) | < 0.001 |
| Fracture type (intertrochanteric vs. neck) | 1.97 (0.66–6.52) | 0.226 | 1.23 (0.57–2.68) | 0.595 | 1.62 (0.94–2.80) | 0.083 |
| Surgery type (fixation vs. arthroplasty) | 1.81 (0.59–6.70) | 0.306 | 1.10 (0.51–2.45) | 0.816 | 1.15 (0.67–1.99) | 0.604 |
| Time to surgery (per 1 day increase) | 1.10 (0.83–1.30) | 0.411 | 1.10 (1.01–1.17) | 0.023 | 1.14 (1.08–1.19) | < 0.001 |
| Albumin (< 3.5 g/dL vs. ≥ 3.5 g/dL) | 4.77 (1.59–15.79) | 0.006 | 4.27 (1.97–9.53) | < 0.001 | 2.52 (1.46–4.32) | 0.001 |
| SII (per 100 units) | 1.16 (1.05–1.28) | 0.003 | 1.11 (1.04–1.19) | 0.004 | 1.12 (1.07–1.18) | < 0.001 |
Abbreviation: HR Hazard ratio, CI Confidence interval, CCI Charlson comorbidity index, SII Systemic immune-inflammation index