Table 1.
Baseline characteristics of all BC patients with BM and PSM patients
| Category | All patients | Non-surgery (%) | P value | PSM patients | Non-surgery (%) | P value |
|---|---|---|---|---|---|---|
| Surgery (%) | Surgery (%) | |||||
| Age | 0.000 | 0.467 | ||||
| < 51 | 422 (29.0) | 610 (24.4) | 281 (28.6) | 282 (26.9) | ||
| 51–78 | 916 (63.0) | 1599 (63.9) | 676 (64.6) | 659 (62.9) | ||
| > 78 | 116 (8.0) | 293 (11.7) | 90 (8.6) | 106 (10.1) | ||
| Race | 0.881 | 0.153 | ||||
| Black | 218 (15.0) | 390 (15.6) | 160 (15.3) | 142 (13.6) | ||
| Other | 114 (7.8) | 196 (7.8) | 72 (6.9) | 93 (8.9) | ||
| White | 1122 (77.2) | 1916 (76.6) | 815 (77.8) | 812 (77.6) | ||
| Sex | 0.067 | 0.394 | ||||
| Female | 1426 (98.1) | 2472 (98.8) | 1032 (98.6) | 1027 (98.1) | ||
| Male | 28 (1.9) | 30 (1.2) | 15 (1.4) | 20 (1.9) | ||
| Primary site | 0.534 | 0.988 | ||||
| Central portion | 157 (10.8) | 241 (9.6) | 107 (10.2) | 104 (9.9) | ||
| Upper-inner | 149 (10.2) | 233 (9.3) | 106 (10.1) | 103 (9.8) | ||
| Lower-inner | 75 (5.2) | 145 (5.8) | 58 (5.5) | 62 (5.9) | ||
| Upper-outer | 495 (34.0) | 906 (36.2) | 366 (35.0) | 377 (36.0) | ||
| Lower-outer | 114 (7.8) | 196 (7.8) | 79 (7.5) | 81 (7.7) | ||
| Others | 464 (31.9) | 781 (31.2) | 331 (31.6) | 320 (30.6) | ||
| Laterality | 0.512 | 0.457 | ||||
| Left | 772 (53.1) | 1293 (51.6) | 548 (52.3) | 565 (54.0) | ||
| Right | 682 (46.9) | 1209 (48.3) | 499 (47.7) | 482 (46.0) | ||
| Histological type | 0.007 | 0.931 | ||||
| Ductal | 1143 (78.6) | 1971 (78.8) | 841 (80.3) | 845 (80.7) | ||
| Lobular | 264 (18.2) | 402 (16.1) | 170 (16.2) | 169 (16.1) | ||
| Others | 47 (3.2) | 129 (5.2) | 36 (3.4) | 33 (3.2) | ||
| Grade | 0.000 | 0.550 | ||||
| I | 111 (7.6) | 255 (10.2) | 87 (8.3) | 90 (8.6) | ||
| II | 593 (40.8) | 1261 (50.4) | 478 (45.7) | 455 (43.5) | ||
| III | 747 (51.4) | 975 (39.0) | 479 (45.7) | 501 (47.9) | ||
| IV | 3 (0.2) | 11 (0.4) | 3 (0.3) | 1 (0.01) | ||
| T stage | 0.000 | 0.567 | ||||
| T1 | 178 (12.2) | 371 (14.8) | 133 (12.7) | 134 (12.8) | ||
| T2 | 650 (44.7) | 971 (38.8) | 458 (43.7) | 475 (45.4) | ||
| T3 | 307 (21.1) | 471 (18.8) | 206 (19.7) | 181 (17.3) | ||
| T4 | 319 (21.9) | 689 (27.5) | 250 (23.9) | 257 (25.4) | ||
| N stage | 0.000 | 0.544 | ||||
| N0 + N1 | 779 (53.0) | 2069 (82.7) | 715 (68.3) | 702 (67.0) | ||
| N2 + N3 | 684 (47.0) | 433 (17.3) | 332 (31.7) | 345 (33.0) | ||
| Radiotherapy | 0.000 | 0.861 | ||||
| No | 686 (47.2) | 1605 (64.1) | 556 (53.1) | 560 (53.5) | ||
| Yes | 768 (52.8) | 897 (35.9) | 491 (46.9) | 487 (46.5) | ||
| Chemotherapy | 0.000 | 0.249 | ||||
| No | 519 (35.7) | 1235 (49.4) | 422 (40.3) | 448 (42.8) | ||
| Yes | 935 (64.3) | 1267 (50.6) | 625 (59.7) | 599 (57.2) | ||
| Brain metastasis | 0.000 | 0.404 | ||||
| No | 1419 (97.6) | 2322 (92.8) | 1014 (96.8) | 1007 (96.2) | ||
| Yes | 35 (2.4) | 180 (7.2) | 33 (3.2) | 40 (3.8) | ||
| Liver metastasis | 0.000 | 0.448 | ||||
| No | 1261 (86.7) | 1858 (74.3) | 877 (83.8) | 864 (82.5) | ||
| Yes | 193 (13.3) | 644 (25.7) | 170 (16.2) | 183 (17.5) | ||
| Lung metastasis | 0.000 | 0.162 | ||||
| No | 1240 (85.3) | 1817 (72.6) | 863 (82.4) | 838 (80.0) | ||
| Yes | 214 (14.7) | 685 (27.4) | 184 (17.6) | 209 (20.0) | ||
| Tumor size, cm | 0.004 | 0.829 | ||||
| < 2 | 157 (10.8) | 362 (14.5) | 124 (11.8) | 125 (11.9) | ||
| 2–5 | 796 (54.7) | 1333 (53.3) | 572 (54.6) | 584 (55.8) | ||
| > 5 | 501 (34.5) | 807 (32.3) | 351 (33.5) | 338 (32.3) | ||
| Breast subtype | 0.023 | 0.889 | ||||
| HR−/HER2+ | 91 (6.3) | 153 (6.1) | 62 (5.9) | 69 (6.6) | ||
| HR+/HER2- | 963 (66.2) | 1703 (68.1) | 705 (67.3) | 695 (66.4) | ||
| HR+/HER2+ | 231 (15.9) | 429 (17.1) | 171 (16.3) | 168 (16.0) | ||
| HR−/HER2- | 169 (11.6) | 217 (8.7) | 109 (10.4) | 115 (11.0) | ||
| Insurance status | 0.000 | 0.128 | ||||
| Uninsured | 32 (2.2) | 123 (4.9) | 27 (2.5) | 17 (1.6) | ||
| Insured | 1422 (97.8) | 2379 (95.1) | 1020 (97.4) | 1030 (98.4) | ||
| Marital status | 0.000 | 0.760 | ||||
| Unmarried | 688 (47.3) | 1354 (54.1) | 529 (50.5) | 522 (49.9) | ||
| Married | 766 (52.7) | 1148 (45.9) | 518 (49.5) | 525 (50.1) |
BC breast cancer, BM bone metastases, PSM propensity score matching