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. 2021 Mar 4;14:57. doi: 10.1186/s13068-021-01911-3

Table 3.

Equipment specifications, installed equipment costs and fixed capital investment

Code Type Size Units Material Number f.o.b. ($, unit cost) FBM CBM ($, unit cost) CBM ($) Source the calculation was based on

Area 100 media preparation

 + 

fermentation

V-101 Mixing tank 200 m3 SS304 1 173,977 1.80 313,159 313,159 [40]
A-101 Agitator 5.51 kW SS 1 31,560 1.50 47,340 47,340 [41]
M-101 In-line mixer 50 m3/h SS316 1 41,271 1.70 70,161 70,161 [41]
P-101 Centrifugal pump 29.41 kW SS316 1 28,467.39 2.30 65,475 65,475 [32, 41]
HE-101 Heat exchanger (shell and tube) 470.25 m2 SS314 1 295,594.85 3.29 972,507 972,507 [40]
HE-102 Heat exchanger (shell and tube) 11.66 m3 SS314 1 23,326.98 3.29 76,746 76,746 [40]
HT-101 Holding tube

L = 120

D = 0.4

Sch. 40 pipe

m

m

SS314 1 308,766.0516 2 617,532 617,532 [42]
P-102 Centrifugal pump 29.41 kW SS316 1 47,137.35 2.30 108,416 108,416 [41]
C-101 Centrifugal compressor 1468.46 kW CS 1 1,240,647.12 1.60 1,985,035 1,985,035 [40]
F-101 Filter - - - 1 - - 14,199 14,199 [32]
F-102 Filter - - - 1 - - 93,561 93,561 [32]
HE-103 Compressor cooler 28.90 m2 CS 1 21,291.23 3.29 70,048 70,048 [40]
R-101 ALB (bioreactor) 1000 m3 SS316 1 - - 991,615 991,615 [38]
HE-104 Bioreactor Chiller 744.00 m2 SS316 1 458,438.06 3.29 1,508,261 1,508,261 [40]

Area 200

Downstream

Processing

P-201 Pump (discharging) 185.19 kW SS 1 29,585.37 2.30 68,046 68,046 [41]
HE-201 Pasteuriser 16.39 m2 SS316 1 42,287.66 3.29 139,126 139,126 [31]
V-201 Holding tank 400.00 m3 SS316 3 173,977.37 1.80 313,159 939,478 [40, 43]
A-201 Agitator 5.51 kW SS 3 35,816.69 1.50 53,725 161,175 [41]
P-202 Pump 80.00 m3/h SS316 3 45,432.38 2.30 104,494 313,483 [41]
RF-201 Rotary vacuum filter 200.00 m2 1 414,134.36 1.4 617,428 617,428 [31, 44]
P-203 Pump 148.15 kW SS316 1 28,467.39 2.30 65,475 65,475 [40]
D-201 Spray dryer SS316 1 - - 1,110,098 1,110,098 [39]
P-204 Pump 29.41 kW SS316 1 28,467.39 2.30 65,475 65,475 [41]
C-201 Fan 17.54 kW CS 1 16,156.00 1.60 40,088 40,087.79 [42, 45]
HE-202 Air heater 105.39 m2 SS316 1 44,020.54 3.29 144,828 144,827.56 [40]
V-202 Mixing tank 100 m3 SS316 1 166,792.77 1.80 300,227 300,227 [40]
A-202 Agitator 5.51 kW SS 1 31,560.16 1.50 47,340 47,340 [41]
P-205 Pump 29.41 kW SS316 1 28,467.39 2.30 65,475 65,475 [41]
HG-201 Homogeniser 45 m3/h SS316 1 184,065.28 2.06 429,432 429,432 [46]
P-206 Pump 29.41 kW SS316 1 28,467.39 2.30 65,475 65,475 [41]
CS-201 Centrifugal separator 0.686 m3/h Ss316 1 442,391.50 1.3 575,109 575,109 [39, 46]
E-201 Evaporator (single effect/agitated film, scrapped wall) 20.66 m2 SS 1 293,102.88 2.50 732,757 732,757 [40]
SL-201 Concrete silo 1500 m3 Concrete 1 88,294.62 1.70 150,101 150,101 [41, 46]
V-203 Holding tank 800 m3 SS304 1 244,559.38 1.80 440,207 440,207 [40]
FCI (1.2xCBM) 16,085,855