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. 2021 Feb 19;11:623726. doi: 10.3389/fimmu.2020.623726

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Copyright © 2021 Sørensen, Park, Gong, Vasanth, Dahle, Korsnes, Phuong, Kiron, Øyen, Pittman and Sørensen

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Phagocytosis of head kidney macrophage-like cells from Atlantic salmon fed different experimental diets. BG1: Fishmeal + Fish oil diet; BG2: Soybean meal diet; BG3: Fishmeal + Plant oil diet; BG4: Plant ingredients + Fish oil diet; BG5: Plant ingredients + Plant oil diet. (A) Percent of phagocytic cells. (B) mean number of particles ingested per phagocytic cell. (C) Representative cell images indicate cells with no BP, SB, and 1BP, 2BP, and >3BP. Statistically significant differences (p < 0.05) between dietary groups are indicated by different letters. Bar plots show mean ± SD, n = 6. All cell images were captured with 40× objective. Scale bar = 10 µm. SB, surface-binding particles; 1 BP, 2 BP, and > 3 BP, one to three internalized bio-particles; BF, brightfield.