Table 1. The demographic characteristics of patients included in this study.

	Patients	Tissue samples	Gender	Disease	Age	Literality	RB1 mutation	ctDNA conc.
	1		Female	RB	20 months	unilateral	Negative	0.23
	2	obtained	Male	RB	7 months	bilateral	Positive	0.43
	3		Male	RB	15 months	bilateral	Positive	0.76
	4	obtained	Male	RB	2 months	bilateral	Positive	0.93
	5		Female	RB	16 months	unilateral	Negative	0.19
	6		Male	RB	6 months	bilateral	Negative	0.92
	7	obtained	Female	RB	9 months	unilateral	Positive	5.39
	8		Female	RB	16 months	unilateral	Negative	2.57
	9	obtained	Female	RB	21 months	unilateral	Negative	0.77
	10		Male	RB	21 months	unilateral	Negative	7.26
	11		Male	RB	10 months	bilateral	Positive	10.2
	12	obtained	Female	RB	5 months	unilateral	Negative	5.37
	13		Female	RB	24 months	unilateral	Positive	29.4
	14		Female	RB	13 months	bilateral	Positive	16.3
	15		Male	RB	8 months	bilateral	Positive	0.86
	16		Male	congenital glaucoma	17 months	NA	NA	0.12
	17		Male	congenital glaucoma	20 months	NA	NA	0.14
	18		Female	pediatric cataract	4 years	NA	NA	0.09
	19		Female	pediatric cataract	5 years	NA	NA	0.17
	20		Male	pediatric cataract	8 years	NA	NA	0.17