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. 2021 Feb 15;17:439–460. doi: 10.3762/bjoc.17.40

Figure 12.

Figure 12

Ribbon representation of the X-ray crystal structures of proteins containing fluoroprolines. A) Enhanced green fluorescent protein (pdb: 2q6p), B) collagen mimicking model (pdb: 3ipn), only one fluoroproline residue is shown, C) KlenTag DNA polymerase (pdb: 4dle) and D) thioredoxin A (pdb: 4hua and 4hu9). All C4-endo- and undefined puckers are labeled accordingly, assuming that the rest of the residues adopt the exo-pucker conformation. All cis-amide positions are labeled as well, assuming the default arrangement being trans.