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. 2021 Jan 25;6(2):e145029. doi: 10.1172/jci.insight.145029

Figure 3. Quantitative analysis of the arrangement of cones in retinas in the presence and absence of Nrf2 overexpression in the RPE.

Figure 3

(A) Plot showing the surface area of craters as a percentage of total surface area in retinal flat mounts treated with AAV-Best1-Nrf2 and AAV-hRedO-GFP-H2b compared with control (AAV-hRedO-GFP-H2b only) in P40-P60 mice. Area was measured at the outer, apical retinal surface (n = 9 mice). (B) Plot showing the number of craters counted in each retina flat mount from the same conditions (n = 9 mice). Data shown as mean ± SD. P < 0.005 by paired t test.