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. 2021 Jan 25;6(2):e135626. doi: 10.1172/jci.insight.135626

Figure 2. Characterization of serum from mice with a liver-specific double KO of Cpt2 and Atgl.

Figure 2

(A) Serum metabolites in mice under fed and fasted conditions (n = 6). (B) mRNA of hepatokines in livers of mice in fed and fasted states were measured by quantitative reverse-transcription-PCR (n = 6). (C) ELISA of hepatokine levels in ng/mL in serum of fasted mice (n = 6). One- or 2-way ANOVA followed by Tukey’s multiple-comparison test were performed where appropriate to detect significance between genotypes. Single letter denotes P < 0.05. Double letters denote P < 0.01. Letters w (control), a (Atgl), c (Cpt2), d (DKO), and p (Pparα) represent significance between the genotypes. Data are shown as mean ± SEM.