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. 2021 Feb 8;6(3):e145761. doi: 10.1172/jci.insight.145761

Figure 6. Activation of intrahepatic type I IFN signaling enhances HBV-specific CD8+ T cell responses irrespective of antigen specificity.

Figure 6

HBV-Tg mice were adoptively transferred with ENV28-specific naive CD8+ T cells and treated with PIC-LNPs or NaCl on day 4 (n = 5 for each group). (A) ENV28-specific CD8+ T cell responses in the liver were analyzed on day 7 after transfer. (B) Serum ALT levels were measured on days 0 and 7. Results are representative of 2 independent experiments. Data represent mean ± SD. P values determined by Student’s t test (1 sided, unpaired). **P < 0.01, ***P < 0.001.