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. 2021 Mar 5;30(5):1099–1107. doi: 10.1007/s00044-021-02715-8

Table 2.

Results from the molecular docking; mean ΔG in kcal/mol of the top 5 docking poses (standard deviation, median) for miglitol (standard) and compounds 8 and 16

Enzyme Miglitol 8 16
Geobacillus sp. (α-glucosidase) −3.81 (0.11, −3.82) −4.22 (0.05, −4.22) −4.66 (0.31, −4.64)
Baker’s yeast (α-glucosidase) −3.62 (0.48, −3.30) −4.21 (0.02, −4.20) −4.50 (0.10, −4.49)
Rice (β-glucosidase) −5.12 (0.27, −5.01) −5.53 (0.11, −5.52) −5.32 (0.22, −5.39)
White clover (α-galactosidase) −4.81 (0.01, −4.82) −5.34 (0.10, −5.32) −5.56 (0.07, −5.57)
E. coli (β-galactosidase) −5.19 (0.17, −5.10) −5.61 (0.15, −5.71) −5.68 (0.14, −5.62)