Figure 6. .

Community reorganization was temporally localized to ovulation. Changes in community assignment (A) were coordinated and closely tracked the timing of spikes in estradiol concentrations (B). Default mode, limbic, subcortical, and temporoparietal networks exhibited peaks in flexibility on Day 23, indicating brain-wide functional reorganization during the ovulatory window. These same networks also exhibited elevated flexibility between Days 5 and 10 during the secondary estradiol peak. The pattern of flexibility shown here corresponds to the network reorganization observed for dynamic community detection performed with the parameter combination ω = 0.9, γ = 1.055 (blue outline in Figure 2). Here, flexibility is calculated over a five-day sliding window.