Table 3.
Association of ECG parameters with myocardial fibrosis. ECG variables added one at a time to the clinical model in multivariate logistic regression analysis.
| Predicting Myocardial Fibrosis (ECV ≥ 29% or LGE) | ||
|---|---|---|
| OR (95% CI) | p value | |
| Clinical Variables | ||
| Age | 1.00 (0.98–1.02) | .99 |
| Hypertension | 2.32 (1.20–4.49) | .01 |
| Heart failure | 3.76 (1.83–7.72) | <.001 |
| Female gender | 0.59 (0.33–1.03) | .06 |
| ECG variables | ||
| Heart rate > 70 bpm | 1.48 (0.83–2.62) | .18 |
| QRS duration (continuous) | 0.99 (0.97–1.02) | .57 |
| QRS duration > 100ms | 1.05 (0.50–2.22) | .89 |
| Cornell voltage (continuous) | 1.04 (0.99–1.09) | .09 |
| Cornell voltage > 2.0 mV | 2.22 (0.93–5.30) | .07 |
| QTc duration (continuous) | 1.004 (0.99–1.01) | .23 |
| QTc duration > 450 ms | 1.26 (0.65–2.44) | .50 |
| TW amplitude (continuous) | 0.08 (0.01–0.48) | .006 |
| TW amplitude ≤ 200µV | 1.95 (1.09–3.49) | .03 |
Abbreviations: ECG, electrocardiogram; ECV, extracellular volume fraction; LGE, late gadolinium enhancement; QTc, corrected QT; TW amplitude, T‐wave amplitude.