Table 3.
Selected screening studies for atrial fibrillation using newer technologies
| Device | Author, year | Setting | Inclusion criteria | N | Mean age (yrs) | Duration of monitoring | New AF detection (%) | |
|---|---|---|---|---|---|---|---|---|
| Handheld ECG device | Zenicor SL | Berge et al. (2018) | Norway systematic | Age 63‐65 yrs,_ CHADS‐VaSC≥2 (M) or ≥3 (F) | 1510 | 64 |
10 sec Twice daily for 2 weeks |
0.9% |
| Zenicor SL | Svennberg et al. (2015) | Sweden systematic | Age 75 to 76 yrs, | 7173 | 75 |
10 sec Twice daily for 2 weeks |
3.0% | |
| Zenicor SL | Engdahl, Andersson, Mirskaya, and Rosenqvist (2013) | Sweden systematic | Age 75 to 76 yrs, + CHADS2 risk score≥2 | 403 | 75 |
10 sec Twice daily for 2 weeks |
7.4% | |
| Zenicor SL | Kemp Gudmundsdottir et al. (2020) | Sweden systematic | Age 75‐76 yrs + NTproBNP≥125 ng/l | 3766 | 75 |
10 sec Twice daily for 2 weeks |
4.4% | |
| Zenicor SL | Doliwa et al. (2012) |
Sweden Postdischarge |
Recent ischemic stroke/TIA and no prior AF | 249 | 72 |
10 sec 30 days |
4.8% | |
| My Diagnostick | Tieleman et al. (2014) | Netherlands | Influenza vaccination | 676 | 74 | 1 min | 1.6% | |
| My Diagnostick | Kaasenbrood et al. (2020) |
Netherlands Primary care Opportunistic |
Age>65 years | 919 | 1 min | 1.43% | ||
| My Diagnostick SL | Tavernier et al. (2018) |
Belgium Geriatric ward |
Geriatric | 252 | 84 | Daily 1 min during hospitalization (median 5 ) | 13% | |
| ECG Patch | ZioPatch iRhythm | Turakhia et al. (2015) (STUDY‐AF) | US | M, age≥65 yrs and ≥risk factors | 75 | 69 | Two weeks continuous | 5.3% |
| ZioPatch iRhythm | Steinhubl et al. (2018) |
US National health plan members |
Age≥75 yrs or M>55/F>65 years+risk factors | 2659 | 72 | Continuous 4 weeks | 2.4% | |
| Zio XT Patch |
Rooney et al. (2019) ARIC study |
US Community surveillance study |
No prior AF | 386 | 79 | Continuous 2‐4 weeks |
2.5% (2 weeks) 4% (4 weeks) |
|
| Zio Patch |
Heckbert et al. (2018) Multi‐Ethnic Study of Atherosclerosis |
US Community surveillance study |
No prior AF | 804 | 75 | Continuous 2‐4 weeks | 4% (AF/AFL) | |
| Smartphone ECG‐based | AliveCor Kardia Mobile SL |
Lowres et al. (2014) (SEARCH‐AF) |
Australia Pharmacy Opportunistic |
Age≥65 years | 1000 | 76 | 30 sec | 1.5% |
|
AliveCor Kardia Mobile SL |
Chan et al. (2016) | Hong Kong Outpatient clinic | Age ≥65 years or HTN/diabetes | 1013 | 68 | 30 sec | 0.5% | |
| AliveCor KardiaMobile SL |
Halcox et al. (2017) (REHEARSE AF) |
UK Randomized trial |
Age≥65 years +CHA2DS2‐VASc≥2 | 1001 | 73 |
30 sec Twice weekly for 1 year |
3.8% | |
| Smartphone device PPG‐based | Cardio Mobile app | Chan et al. (2016) |
Hong Kong Outpatient |
Age years ≥65 or HTN | 1013 | 68 | 30 sec | 0.5% |
| Huawei wristband (Honor Band 4) or Huawei Watch | Guo et al. (2019) | General population across China | Age > 18 yrs | 187,912 | 35 | ≥14 days | 0.23% | |
| Smartwatch | Apple smartwatch, iPhone app | Perez et al. (2019) | General population across USA | Age > 22 yrs | 419,297 | 41 |
Median 117 days |
0.52% irregular heart rhythm |
Abbreviations: AF, atrial fibrillation; AFL, atrial flutter; F, females; HTN, hypertension; M, males; TIA, transient ischaemic attack; Yrs, years.