Table 3. Folding performance of CASP free modeling protein targets on 40 CASP12 and CASP13 free modeling target domains.

Values in bold represent the best performance.

Method	Mean TM-score	Median TM-score	# TM-scores > 0.5
DConStruct	0.46	0.50	20/40
DMPfold	0.42	0.38	15/40
GDFuzz3Da	0.41	0.39	9/28
CGLFoldb	0.40	0.43	8/29
CONFOLD2	0.38	0.32	10/40
ROSETTA	0.37	0.36	6/40

^a GDFuzz3D results are reported for 28 CASP free modeling target domains having length less than 400 residues, obtained by submitting jobs to its web server, which is limited to protein target residues less than 400 residues.

^b CGLFold results are adopted directly from the published results containing 29 CASP free modeling target domains.