Table 4. Folding performance of DConStruct using trRosetta-predicted distance maps compared to top CASP predictors and trRosetta distance-only modeling on 40 CASP12 and CASP13 free modeling target domains.
Method | Mean TM-score | Median TM-score | # TM-scores > 0.5 |
---|---|---|---|
A7Da | 0.60 | 0.61 | 12/17 |
DConStruct (with trRosetta distance maps) | 0.49 | 0.51 | 21/40 |
Zhangb | 0.44 | 0.44 | 12/39 |
BAKERb | 0.43 | 0.41 | 13/39 |
trRosetta (distance-only) | 0.42 | 0.34 | 12/40 |
MULTICOMb | 0.42 | 0.4 | 10/39 |
Zhang-Server | 0.41 | 0.42 | 12/40 |
Jones-UCLb, c | 0.39 | 0.37 | 10/38 |
RaptorX-Contact | 0.38 | 0.35 | 9/40 |
BAKER-ROSSETASERVER | 0.35 | 0.34 | 4/40 |
a A7D results contain only 17 CASP13 free modeling target domains.
b CASP human groups’ results do not include the server-only target T0950-D1.
c Jones-UCL results additionally do not include the target T0869-D1 due to missed submission.