Table 1: NK panel.
Markers are ordered according to the isotopic mass of the metal to which they were conjugated. 191Ir/193Ir is the natural abundance of the nucleic acid intercalator. 194Pt/195Pt is the natural abundance of cisplatin.
| Specificity | Clone | Isotope | Purpose | Surface/Intracellular |
|---|---|---|---|---|
| CD57 | HCD57 | 89Y | Maturity/Memory | surface |
| CD45 | HI30 | 102Pd, 104Pd, 106Pd, 108Pd | Barcoding | surface |
| HLA-DR | Tü36 | Qdot 655 (112Cd-114Cd) | Activation/Lineage | surface |
| CD3 | UCHT | 115In | T cell lineage | surface |
| CD38 | HIT2 | 141Pr | Activation Marker | surface |
| CD69 | FN50 | 142Nd | Activation Marker | surface |
| CD33 | WM53 | 143Nd | Monocyte lineage | surface |
| CD14 | M5E5 | 143Nd | Myeloid lineage | surface |
| CD2 | RPA-2.10 | 144Nd | Activation/Maturity | surface |
| LILRB1 | MAB20172 | 145Nd | Inhibitory Receptor | surface |
| CD19 | HIB19 | 146Nd | B cell lineage | surface |
| CD8 | SK1 | 147Sm | T cell lineage and NK cell Activation/Maturity | surface |
| FcRg | polyclonal | 148Nd | Maturity/Adaptive | intracellular |
| CD4 | SK3 | 149Sm | T cell lineage | surface |
| Syk | 4D10.2 | 150Nd | Signaling | intracellular |
| CD62L | DREG-56 | 151Eu | Activation | surface |
| ki-67 | Ki-67 | 152Sm | Proliferation | intracellular |
| KIR2DS4 | 179315 | 153Eu | Activating Receptor | surface |
| NKp46 | 9.00E+02 | 155Gd | Activating Receptor | surface |
| NKG2D | 1D11 | 156Gd | Activating Receptor | surface |
| TIGIT | 741182 | 157Gd | Inhibitory Receptor | surface |
| 2B4 | C1.7 | 158Gd | Activating Receptor | surface |
| DNAM-1 | DX11 | 159Tb | Activating Receptor | surface |
| FAS-L | NOK-1 | 160Gd | Apoptosis | surface |
| NKp30 | P30-15 | 161Dy | Activating Receptor | surface |
| Siglec-7 | S7.7 | 162Dy | Inhibitory Receptor | surface |
| NKG2C | 134522 | 163Dy | Maturity/Memory | surface |
| NKp44 | P44-8 | 164Dy | Activating Receptor | surface |
| CD96 | NK92.39 | 165Ho | NKG2 Co-receptor | surface |
| KIR2DL1/KIR2DS5 | 143211 | 166Er | Inhibitory Receptor | surface |
| CD94 | DX22 | 167Er | Activating Receptor | surface |
| CXCR6 | K041E5 | 168Er | Memory | surface |
| PD1 | EH12.2H7 | 169Tm | Inhibitory Receptor | surface |
| KIR2DL5 | UP-R1 | 170Er | Inhibitory Receptor | surface |
| NKG2A | 131411 | 171Yb | Inhibitory Receptor | surface |
| NTB-A | NT-7 | 172Tb | Activating Receptor | surface |
| KIR3DL1 | DX-9 | 173Yb | Inhibitory Receptor | surface |
| CD56 | NCAM16.2 | 174Yb | NK cell lineage | surface |
| KIR2DL3 | 180701 | 175Lu | Inhibitory Receptor | surface |
| Perforin | B-D48 | 176Yb | Cytolytic Protein | intracellular |
| DNA-1/DNA-2 | NA | 191Ir/193Ir | Nucleated cells | surface |
| Cisplatin | NA | 194Pt/195Pt | Viability | surface |
| CD16 | 3G8 | 209Bi | FcgRIII receptor | surface |