. 2021 Mar 5;16(3):e0248168. doi: 10.1371/journal.pone.0248168

Table 3. Haplotype frequencies of selected SNPs in HOTAIR gene between endometriosis patients and controls.

SNPs^a	Genotype/allele	No. (%) of patients	No. (%) of controls	p-value^b	Corrected p-value^c	OR (95% CI)^a
rs1838169	GG	130	73	0.0004^***	0.0024^**	1.7342 (1.2760–2.3571)
rs4511324	CG	64	53	0.6171	1.0000	1.1013 (0.7538–1.6090)
	GA	88	66	0.2222	1.0000	1.2331 (1.2331–1.7269)
	CA	498	514	0.0002^***	0.0012^**	0.6597 (0.5289–0.8228)
rs1838169	GG	129	69	<0.0001^***	0.0003^***	1.8463 (1.3512–2.5229)
17720428	GT	85	63	0.1884	1.0000	1.2589 (0.8932–1.7742)
	CG	69	55	0.4348	1.0000	1.1582 (0.8000–1.6768)
	CT	489	517	<0.0001^***	0.0002^***	0.6250 (0.5004–0.7806)
rs4511324	GG	130	73	0.0002^***	0.0012^**	1.7939 (1.3215–2.4351)
17720428	GT	70	63	0.8065	1.0000	1.0437 (0.7313–1.4896)
	AG	74	63	0.5657	1.0000	1.1093 (0.7805–1.5767)
	AT	538	561	0.0011^**	0.0066^**	0.9355 (0.7445–1.1754)

^aAbbreviations: SNP, single-nucleotide polymorphism; OR, odds ration; 95% CI, 95% confidence interval.

^bp-values were calculated by χ2 test.

^cBonferroni correction was applied to get the corrected p-value, which equals to p-value×6. Statistical significance

*, p-value <0.05

**, p-value <0.01

***, p-value <0.001.