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. 2021 Jan 30;72(5):e120–e127. doi: 10.1093/cid/ciaa1773

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© The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Azithromycin-resistant Salmonella Typhi in a global context. The diagram depicts a maximum likelihood rooted phylogenetic tree with a final alignment of 25 832 chromosomal SNVs for 3472 globally representative isolates, including all publicly available isolates from India. The color of the internal branches represents the genotype, the colored ring around the tree indicates the country or region of origin for each isolate, and the blue stars indicate which isolates originate from this study. Additionally, the tree contains each known S. Typhi isolate with an acrB mutation in public databases, these originate from India, Nepal, Bangladesh, and Pakistan. The location of the XDR isolates from Pakistan are added for context. Abbreviations: AzithroR, azithromycin resistant; SNV, single nucleotide variant; XDR, extensively drug-resistant.