Table 1.
Nursing Home Resident Cohort Characteristics and Exposures, 2012–2017
| Variable | Cohort resident-days (000s)a | C. difficile infection (N) | Incidence Rate per 100 000 resident-days (95% CI) |
|---|---|---|---|
| Total | 134 145 (100%) | 1708 (100%) | 1.27 (1.21, 1.34) |
| Age | |||
| 66 to 75 | 16 144 (12.0%) | 223 (13.1%) | 1.38 (1.21, 1.58) |
| 76 to 85 | 44 666 (33.3%) | 617 (36.1%) | 1.38 (1.27, 1.49) |
| ≥86 | 73 335 (54.7%) | 868 (50.8%) | 1.18 (1.11, 1.27) |
| Female | 95 782 (71.4%) | 1119 (65.5%) | 1.17 (1.10, 1.24) |
| Hospital visit in prior 31–90 db | |||
| None | 120 950 (90.2%) | 972 (56.9%) | .80 (.75, .86) |
| Any | 13 195 (9.8%) | 736 (43.1%) | 5.58 (5.18, 6.00) |
| 1 to 7 d | 10 006 (7.5%) | 489 (28.6%) | 4.89 (4.46, 5.34) |
| ≥8 d | 3140 (2.3%) | 247 (14.5%) | 7.87 (6.92, 8.91) |
| Charlson comorbidities | |||
| 0 | 90 962 (67.8%) | 662 (38.8%) | .73 (.67, .79) |
| 1 | 18 381 (13.7%) | 291 (17%) | 1.58 (1.41, 1.78) |
| 2 to 3 | 17 721 (13.2%) | 478 (28%) | 2.70 (2.46, 2.95) |
| ≥4 | 7080 (5.3%) | 277 (16.2%) | 3.91 (3.47, 4.40) |
| History of C. difficile infection | 1989 (1.5%) | 312 (18.3%) | 15.7 (14.0, 17.5) |
| Acid suppressants in prior 90 d | |||
| Proton pump inhibitor | 52 915 (39.4%) | 933 (54.6%) | 1.76 (1.65, 1.88) |
| H2 antagonist | 4732 (3.5%) | 91 (5.3%) | 1.92 (1.55, 2.36) |
| Device use in prior 30 d | |||
| Feeding tube | 958 (0.7%) | 80 (4.7%) | 8.35 (6.62, 10.4) |
| Dialysis | 654 (0.5%) | 58 (3.4%) | 8.87 (6.73, 11.5) |
| Functional status, requires assistance … | |||
| Transferring | 99 413 (74.1%) | 1402 (82.1%) | 1.41 (1.34, 1.49) |
| Dressing | 118 575 (88.4%) | 1576 (92.3%) | 1.33 (1.26, 1.40) |
| Eating | 48 959 (36.5%) | 628 (36.8%) | 1.28 (1.18, 1.39) |
| With hygiene | 112 334 (83.7%) | 1519 (88.9%) | 1.35 (1.29, 1.42) |
| Toileting | 118 800 (88.6%) | 1548 (90.6%) | 1.30 (1.24, 1.37) |
Abbreviation: CI, confidence interval.
aWeighted to reflect the source population (case weight = 1, control weight = 1000).
bNote that residents with a hospital visit in the prior 30 d were excluded from the cohort.