TABLE 3.
Characteristics of graft-injuring events with normal dd-cfDNA and normal creatinine vs abnormal creatinine
Normal creatinine (n = 30) | Abnormal creatinine (n = 21) | P | |
---|---|---|---|
Serum creatinine (mg/dL) | 1.41 | 2.58 | <0.001 |
Allosure (%) | 0.26 | 0.27 | 0.88 |
Mean time from transplant to event (y) | 0.81 | 0.81 | 0.99 |
Tacrolimus level (ng/mL) | 6.88 | 6.62 | 0.70 |
Maintenance immunosuppression (n=) | 0.31 | ||
Tacro + MPA + steroid | 13 | 9 | |
Tacro + MPA | 13 | 7 | |
Tacro + steroid | 2 | 4 | |
Sirolimus + leflunomide | 2 | 0 | |
Sirolimus + leflunomide + steroid | 0 | 1 |
Values expressed as mean when applicable. Student t-test for continuous variables; χ2 test for binary or categorical variables (global P value).
dd-cfDNA, donor-derived cell-free DNA; MPA, mycophenolic acid; Tacro, tacrolimus.