Table 2.
Association Between HOXC11 and LSH Expression and the Clinical Characteristics of 84 Patients with GAC
| Clinicopathologic Characteristics | No.(%) | HOXC11 Expression No.(%) | P | LSH Expression No.(%) | P | ||
|---|---|---|---|---|---|---|---|
| High | Low | High | Low | ||||
| Age | |||||||
| ≥58 | 44 (52.4) | 6 (13.6) | 38 (86.4) | 1.000 | 25 (56.8) | 19 (43.2) | 0.827 |
| <58 | 40 (47.6) | 6 (15.0) | 34 (85.0) | 21 (52.5) | 19 (47.5) | ||
| Gender | |||||||
| Male | 53 (63.1) | 7 (13.2) | 46 (86.8) | 0.753 | 31 (58.5) | 22 (41.5) | 0.496 |
| Female | 31 (36.9) | 5 (16.1) | 26 (83.9) | 15 (48.4) | 16 (51.6) | ||
| Tumor invasion(T) | |||||||
| T1 | 17 (20.2) | 2 (11.8) | 15 (88.2) | 0.439 | 3 (17.6) | 14 (82.4) | 0.005 |
| T2 | 7 (8.4) | 2 (28.6) | 5 (71.4) | 4 (57.1) | 3 (42.9) | ||
| T3 | 27 (32.1) | 2 (7.41) | 25 (92.6) | 16 (59.3) | 11 (40.7) | ||
| T4 | 33 (39.3) | 6 (18.2) | 27 (81.8) | 23 (69.7) | 10 (30.3) | ||
| Lymph node metastasis(N) | |||||||
| N0 | 37 (44.0) | 4 (10.8) | 33 (89.2) | 0.279 | 12 (32.4) | 25 (67.6) | 0.000 |
| N1 | 11 (13.1) | 1 (9.09) | 10 (90.9) | 4 (36.4) | 7 (63.6) | ||
| N2 | 5 (6.0) | 2 (40.0) | 3 (60.0) | 3 (60.0) | 2 (40.0) | ||
| N3 | 14 (16.7) | 1 (7.1) | 13 (92.9) | 14 (100.0) | 0 (0.0) | ||
| Nx | 17 (20.2) | 4 (23.5) | 13 (76.5) | 13 (76.5) | 4 (23.5) | ||
| Metastasis(M) | |||||||
| M0 | 64 (76.2) | 8 (12.5) | 56 (87.5) | 0.467 | 32 (50.0) | 32 (50.0) | 0.132 |
| M1 | 20 (23.8) | 4 (20.0) | 16 (80.0) | 14 (70.0) | 6 (30.0) | ||
| Stage | |||||||
| I | 21 (25.0) | 3 (14.3) | 18 (85.7) | 0.770 | 6 (28.6) | 15 (71.4) | 0.003 |
| II | 23 (27.4) | 2 (8.7) | 21 (91.3) | 10 (43.5) | 13 (56.5) | ||
| III | 20 (23.8) | 3 (15.0) | 17 (85.0) | 16 (80.0) | 4 (20.0) | ||
| IV | 20 (23.8) | 4 (20.0) | 16 (80.0) | 14 (70.0) | 6 (30.0) | ||
| R0 resection | |||||||
| Yes | 73 (86.9) | 10 (13.7) | 63 (86.3) | 0.654 | 37 (50.7) | 36 (49.3) | 0.101 |
| NO | 11 (13.1) | 2 (18.2) | 9 (81.8) | 9 (81.8) | 2 (18.2) | ||
| Postoperative chemotherapy | |||||||
| Yes | 36 (42.9) | 3 (8.33) | 33 (91.7) | 0.314 | 21 (58.3) | 15 (41.7) | 0.668 |
| No | 17 (20.2) | 4 (23.5) | 13 (76.5) | 10 (58.8) | 7 (41.2) | ||
| Uncertain | 31 (36.9) | 5 (16.1) | 26 (83.9) | 15 (48.4) | 16 (51.6) | ||
| Differentiation | |||||||
| Well | 4 (4.7) | 0 (0.0) | 4 (100) | 0.378 | 0 (0.0) | 4 (100.0) | 0.071 |
| Middle | 24 (28.6) | 2 (8.33) | 22 (91.7) | 13 (54.2) | 11 (45.8) | ||
| Poor | 56 (66.7) | 10 (17.9) | 46 (82.1) | 33 (58.9) | 23 (41.1) | ||
| HP | |||||||
| (-) | 52 (61.9) | 6 (11.5) | 46 (88.5) | 0.220 | 28 (53.8) | 24 (46.2) | 0.055 |
| (+) | 13 (15.5) | 1 (7.69) | 12 (92.3) | 4 (30.8) | 9 (69.2) | ||
| Uncertain | 19 (22.6) | 5 (26.3) | 14 (73.7) | 14 (73.7) | 5 (26.3) | ||