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. 2021 Feb 18;11:629026. doi: 10.3389/fphar.2020.629026

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Copyright © 2021 Colomier, Algera and Melchior.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Peppermint oil targeting abdominal pain in IBS. Enteric-coated peppermint oil capsules are released in the small intestine causing a modulation of visceral sensation, smooth muscle relaxation, a modulation of the immune system, and a modulation of the microbiome. The agent is anti-viral and anti-fungal. All proposed mechanisms of action can lead to a decrease in abdominal pain perception. Created with BioRender.com.