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. 2021 Feb 18;11:629026. doi: 10.3389/fphar.2020.629026

FIGURE 4.

FIGURE 4

Predominant symptom-based algorithm for pharmacological treatments in IBS-D 5-HT3-RA, 5-hydroxytryptamine-3 receptor antagonists; IBS, irritable bowel syndrome; IBS-D, IBS with predominant diarrhea; TCA, tricyclic antidepressants; SSRI, serotonin re-uptake inhibitors. Created with BioRender.com.