TABLE 3.

The univariate and multivariate Cox regression analysis between RS and other clinicopathological parameters and OS in dataset 1.

	Univariate cox				Multivariate cox
Parameter	Coef	HR	95%CI	P	Coef	HR	95%CI	P
T stage	1.148	3.151	2.075–4.784	<0.001	0.823	2.278	1.447–3.588	<0.001
N stage	1.233	3.430	1.818–6.472	<0.001	0.334	1.397	0.707–2.758	0.336
M stage	1.444	4.237	2.752–6.524	<0.001	1.056	2.876	1.788–4.625	<0.001
Age	0.450	1.568	1.035–2.376	0.034	0.547	1.729	1.138–2.626	0.010
Gender	0.021	1.021	0.674–1.547	0.921
RS	1.221	3.390	2.145–5.359	<0.001	1.126	3.082	1.913–4.966	<0.001

The median age of ccRCC patients in dataset 1 is 62 years old.