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. 2021 Feb 18;15:638854. doi: 10.3389/fncel.2021.638854

Figure 2.

Figure 2

IDO1 levels and the KYN/TRP ratio were increased in the sera and hippocampi of epileptic mice. (A,B) IDO1 levels in the sera and hippocampi of epileptic mice were evaluated by ELISA. (C,D) The KYN/TRP ratio in the sera and hippocampi of epileptic mice is shown. (E) Double immunofluorescence showing colocalization between IDO1 and GFAP or Iba1 in the hippocampi of epileptic mice (magnification: 400×). The data are presented as the mean ± SEM, n = 3–6 per group. *P < 0.05, **P < 0.01, ***P < 0.001 compared with the control group.