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. 2021 Feb 18;12:618807. doi: 10.3389/fimmu.2021.618807

Figure 1.

Figure 1

CDG abrogates Alt-induced type 2 inflammation and promotes neutrophilia. (A) Intranasal challenge mouse model of innate airway inflammation. (B) Total BAL eosinophils (top) and representative flow plots (bottom). (C) Total lung eosinophils. BAL IL-5 (D) and IL-13 (E) ELISA. (F) Total BAL neutrophils (top) and representative flow plots (bottom). (G) Total lug neutrophils. (H) BAL IFNγ ELISA. (I) BAL IFNβ ELISA 3 h after first challenge. Il7r-/- and Rag2-/- lung eosinophils (J) and BAL IL-5 ELISA (K). Data shown are representative of 2–10 independent experiments with 2–4 mice per group. **P < 0.01, ***P < 0.001, ****P < 0.0001, unpaired t-test.