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. 2021 Feb 18;12:618807. doi: 10.3389/fimmu.2021.618807

Figure 4.

Figure 4

CDG modulation of airway inflammation is STING-dependent and STAT6 independent. (A–D) Wild type and Tmem173-/- mice were challenged using the same model as in Figure 1A. (A) Total lung eosinophils (top) and representative flow plots (bottom). (B) Total lung neutrophils (top) and representative flow plots (bottom). (C) Total lung IL-5+ ILC2s (top) and representative flow plots (bottom). (D) Total lung IFNγ+ ILC1s (top) and representative plots (bottom). (E,F) Wild type and Stat6-/- mice were challenged using the same model as in Figure 1A. (E) Total lung eosinophils (top) and representative flow plots (bottom). (F) Total lung neutrophils (top) and representative flow plots (bottom). Data shown are representative of two independent experiments with 2–3 mice per group. *P < 0.05, **P < 0.01, ****P < 0.0001, unpaired t-test.