Figure 1.

Characterization and preparation of Dex-L and Dex-L-MVs. (A) The size distribution and (B) Zeta potential of the Dex-L measured by dynamic light scattering. (C) The uptake of Dex-FITC at a concentration of 100 μM after different incubation times with macrophages. (D) Mean fluorescence intensity of FITC fluorescently labeled Dex at different concentrations after incubating for 4 h with macrophages. (E) Intracellular Dex-FITC contents measured when the initial FITC fluorescently labeled Dex at the concentrations of 5, 25, 50, and 100 μM. (F) Percentage of Dex-FITC released from Dex-L-MVs at different time points. Mean values of three independent experiments with n = 6 cultures per group and experiment.