Table 1. Blood Glucose Level and Heart Weight/Body Weight.
Control (n = 6) | Linagliptin (n = 6) | Empagliflozin (n = 9) | Combination (n = 7) | |
---|---|---|---|---|
Blood glucose (mg/dL) | ||||
Day 0 | 397 ± 104 | 411 ± 106 | 441 ± 107 | 366 ± 79 |
Day 14 | 598 ± 201 | 494 ± 184 | 320 ± 78* | 300 ± 157* |
Day 35 | 660 ± 206 | 549 ± 180 | 478 ± 95a | 522 ± 85 |
Heart weight/body weight on day 35 (%) | 0.53 ± 0.04 | 0.50 ± 0.03 | 0.47 ± 0.06 | 0.48 ± 0.07 |
*P < 0.05, and aP < 0.10 by one-way analysis of variance with post-hoc comparison using Dunnett’s test.