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. 2021 Mar 6;9(7):2645–2655.e14. doi: 10.1016/j.jaip.2021.02.041

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© 2021 American Academy of Allergy, Asthma & Immunology.

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Figure E5 — CRD and the risk of needing invasive ventilation in the unadjusted model. (A) The cumulative rate of needing invasive mechanical ventilation among patients with or without CRD based on the proportional hazards model. (B) The cumulative rate of needing invasive mechanical ventilation among patients with or without asthma, chronic obstructive pulmonary disease, or bronchiectasis based on the proportional hazards model. (C) The cumulative rate of needing invasive mechanical ventilation among patients with asthma-chronic obstructive pulmonary disease overlap, chronic obstructive pulmonary disease-bronchiectasis overlap, and asthma-bronchiectasis overlap based on the proportional hazards model. (D) Association between the severity of COVID-19, CRD, and the use of invasive mechanical ventilation. The vertical colored bars represented the patient cohort, which was further categorized into different subgroups. The association between the different subgroups was presented with the gray bars, with greater width representing a greater magnitude of overlap. (E) Risk factors predicting the risk of needing invasive mechanical ventilation in patients with COVID-19. Shown are the numbers and percentages of patients with each of the category of disease who needed invasive mechanical ventilation during the study and of patients who did not need invasive mechanical ventilation. CAID, chronic airway inflammatory diseases, which was equivalent to chronic respiratory diseases; CI, confidence interval; COPD, chronic obstructive pulmonary disease; COVID-19, coronavirus disease 2019; CRD, chronic respiratory disease; OR, odds ratio.

Figure E5 — CRD and the risk of needing invasive ventilation in the unadjusted model. (A) The cumulative rate of needing invasive mechanical ventilation among patients with or without CRD based on the proportional hazards model. (B) The cumulative rate of needing invasive mechanical ventilation among patients with or without asthma, chronic obstructive pulmonary disease, or bronchiectasis based on the proportional hazards model. (C) The cumulative rate of needing invasive mechanical ventilation among patients with asthma-chronic obstructive pulmonary disease overlap, chronic obstructive pulmonary disease-bronchiectasis overlap, and asthma-bronchiectasis overlap based on the proportional hazards model. (D) Association between the severity of COVID-19, CRD, and the use of invasive mechanical ventilation. The vertical colored bars represented the patient cohort, which was further categorized into different subgroups. The association between the different subgroups was presented with the gray bars, with greater width representing a greater magnitude of overlap. (E) Risk factors predicting the risk of needing invasive mechanical ventilation in patients with COVID-19. Shown are the numbers and percentages of patients with each of the category of disease who needed invasive mechanical ventilation during the study and of patients who did not need invasive mechanical ventilation. CAID, chronic airway inflammatory diseases, which was equivalent to chronic respiratory diseases; CI, confidence interval; COPD, chronic obstructive pulmonary disease; COVID-19, coronavirus disease 2019; CRD, chronic respiratory disease; OR, odds ratio.