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. Author manuscript; available in PMC: 2021 Mar 6.
Published in final edited form as: Nat Rev Dis Primers. 2020 Jul 16;6(1):58. doi: 10.1038/s41572-020-0188-7

Fig. 3 |. Ventricular action potential and ionic currents.

Fig. 3 |

a | Schematic showing a normal electrocardiogram trace and the corresponding phases of the ventricular action potential (0, 1, 2, 3 and 4) that determine the shape of the trace. b | The major transmembrane ionic currents that generate the ventricular action potential. Inward currents that contribute to depolarization are oriented downwards, and outward currents that contribute to repolarization are oriented upwards; the shapes of the currents indicate their relative intensity. Ito, transient outward potassium current.