| Lactate dehydrogenase (LDH) and S100 calcium-binding protein B (S100B) are suitable serum biomarkers at baseline and during therapy of metastatic melanoma with B-Raf proto-oncogene (BRAF) inhibitors. |
| S100B shows stronger correlation with response and exhibits more accuracy in the prediction of progressive disease as early as 8 weeks before radiographic evidence of progression. |
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