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. Author manuscript; available in PMC: 2022 Mar 4.
Published in final edited form as: Structure. 2020 Dec 23;29(3):213–225.e5. doi: 10.1016/j.str.2020.12.001

Figure 1. HIV-1 Integrase.

Figure 1.

A. Domain Map of HIV-1 Integrase. B. Chemical structures of small molecules used in these studies. C. Open polymer configuration of ALLINI-bound HIV integrase as observed in the IN-GSK1264 crystal structure. D. ALLINI binding site and CCD-CTD interface.