Table 2: Accelerated blistering in FA skin.
Time from negative pressure initiation to first appearance of skin blisters in FA patients (n=8) or age-matched controls (n=9). FA patients showed shorter time to blister formation (median: 21 minutes) compared to matched-controls (median: 41 minutes). Two of the FA patients had undergone bone marrow transplantation but showed no difference in blister formation compared to those FA individuals who did not have a bone marrow transplant. Abbreviations: Comp Group= Complementation Group, BMT= Bone Marrow Transplant; M= Male; F= Female.
| Subject | Gender | Age (years) | Control/FA | Comp Group | BMT | Blistering Time (minutes) |
|---|---|---|---|---|---|---|
| 1 | F | 18 | Control | 31 | ||
| 2 | F | 18 | Control | 41 | ||
| 3 | M | 13 | Control | 48 | ||
| 4 | M | 18 | Control | 41 | ||
| 5 | M | 22 | Control | 33 | ||
| 6 | M | 21 | Control | 48 | ||
| 7 | F | 17 | Control | 45 | ||
| 8 | F | 15 | Control | 40 | ||
| 9 | M | 18 | Control | 43 | ||
| 10 | F | 15 | FA | A | No | 22 |
| 11 | F | 21 | FA | A | Yes | 20 |
| 12 | F | 13 | FA | A | Yes | 22 |
| 13 | M | 12 | FA | C | No | 23 |
| 14 | M | 13 | FA | A | No | 19 |
| 15 | F | 23 | FA | A | No | 16 |
| 16 | M | 23 | FA | A | No | 20 |
| 17 | F | 25 | FA | G | No | 24 |