TABLE 3.
Results of multivariate analysis
| Variable | Hazard ratio | 95% confidence interval | P |
|---|---|---|---|
| ATLL‐prognostic index | |||
| High/intermediate | 3.31 | 1.22‐8.98 | 0.019 |
| Low | 1.00 | ||
| Corrected Ca (mmol/L) | |||
| ≥2.75 | 0.72 | 0.38‐1.36 | 0.306 |
| <2.75 | 1.00 | ||
| PRKCB mutation | |||
| Positive | 1.87 | 1.01‐3.46 | 0.047 |
| Negative | 1.00 | ||
| CD58 copy number loss | |||
| Positive | 3.62 | 1.68‐7.82 | 0.001 |
| Negative | 1.00 | ||
| PRDM1 biallelic alteration | |||
| Positive | 2.86 | 1.07‐7.64 | 0.036 |
| Negative | 1.00 | ||
Seventy‐three patients with evaluable ATLL‐Prognostic Index scores, data of mutation, and copy number alteration were analyzed using Cox's proportional hazard model.