Table 1.
Patient characteristics grouped by rheumatoid arthritis (RA) disease activity (DAS 28).
| Total N = 78 | RA remission N = 33 | Active RA N = 45 | P value | |
|---|---|---|---|---|
| Females (N/%) | 57/73 | 24/73 | 33/73 | 0.95 |
| Age (years) | 57 ± 12 | 57 ± 12 | 58 ± 12 | 0.70 |
| BMI (kg/m2) | 26.1 ± 4.3 | 25.9 ± 4.4 | 26.3 ± 4.4 | 0.67 |
| Smoking status (N/%) | ||||
| Never smokers | 29/37 | 12/36 | 17/38 | 0.74 |
| Former smokers | 35/45 | 17/52 | 18/40 | |
| Current smokers | 14/19 | 4/12 | 8/22 | |
| Oral data | ||||
| Number of teeth | 25 ± 5 | 25 ± 4 | 24 ± 6 | 0.22 |
| PD (mm) | 2.8 ± 0.4 | 2.7 ± 0.3 | 2.8 ± 0.4 | 0.65 |
| CAL (mm) | 3.1 ± 0.8 | 3.0 ± 0.7 | 3.1 ± 0.8 | 0.57 |
| BoP (% of sites) | 31 ± 16 | 33 ± 14 | 30 ± 17 | 0.49 |
| PI (% of sites) | 33 ± 16 | 36 ± 19 | 31 ± 14 | 0.20 |
| Periodontitis (N/%) | ||||
| No | 14/18 | 5/15 | 9/20 | 0.68 |
| Mild/moderate | 50/64 | 23/70 | 27/60 | |
| Severe | 14/18 | 5/15 | 9/20 | |
| RA data | ||||
| RA debut (age) | 43 ± 14 | 41 ± 13 | 45 ± 15 | 0.30 |
| RA duration (years) | 15 ± 11 | 16 ± 12 | 14 ± 11 | 0.29 |
| DAS28 (score) | 3.0 ± 1.1 | 2.1 ± 0.3 | 3.7 ± 1.0 | < 0.001 |
| VAS (score) | 28 ± 21 | 17 ± 14 | 36 ± 21 | < 0.001 |
| MHAQ (score) | 0.37 ± 0.38 | 0.17 ± 0.25 | 0.52 ± 0.39 | < 0.001 |
| RF, ACPA (N/%) | 60/77 | 28/85 | 32/71 | 0.16 |
| Laboratory data | ||||
| ESR (mm/hr) | 19.8 ± 15.5 | 12.7 ± 8.3 | 25.0 ± 17.5 | < 0.001 |
| CRP (mg/L) | 8.8 ± 13.5 | 5.0 ± 10.0 | 11.6 ± 15.1 | 0.031 |
| RF (IU/ml)* | 184 ± 385 | 175 ± 364 | 190 ± 405 | 0.87 |
| TG (mmol/L) | 1.20 ± 0.82 | 1.12 ± 0.65 | 1.26 ± 0.92 | 0.43 |
| TC (mmol/L) | 5.52 ± 1.22 | 5.33 ± 1.02 | 5.64 ± 1.34 | 0.26 |
| HDL-C (mmol/L) | 1.64 ± 0.50 | 1.57 ± 0.44 | 1.69 ± 0.53 | 0.30 |
| LDL-C (mmol/L) | 3.29 ± 0.93 | 3.24 ± 0.76 | 3.33 ± 1.05 | 0.69 |
Categorical/continuous variables of demographic, behavioral and clinical characteristics.
RA disease activity, measured as disease activity score 28 (DAS28); Remission, RA disease in remission defined as DAS28 ≤ 2.6; Active RA disease defined as DAS28 > 2.6; N, number; Age, patient’s age in years at the time of clinical examination; BMI body mass index, PD probing depth, CAL clinical attachment level, BoP bleeding on probing, PI plaque index, DAS28 disease activity score 28, VAS patient global health assessment score on a visual analogue scale, MHAQ modified health assessment questionnaire, RF, ACPA, seropositivity, positive tests for rheumatoid factor (RF) (N = 74) and/or anti-citrullinated protein antibody (ACPA) (N = 77); ESR erythrocyte sedimentation rate, CRP C-reactive protein, TG triglyceride, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol. Analysed with Pearson chi-square and Student t-test: P-level < 0.05. *n = 74.