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. 2021 Mar 5;11:5320. doi: 10.1038/s41598-021-84586-y

Table 2.

Correlation of coagulation proteins with (A) Body mass index (BMI), (B) inflammation (C reactive protein; CRP) and (C) insulin resistance (HOMA-IR), (D) shows the results of the multivariate analysis taking into account BMI, CRP and HOMA-IR.

A. BMI B. CRP C. HOMA-IR D. CRP + BMI + HOMA-IR
p value r2 p value r2 p value r2 p value r2
Antithrombin.III  < 0.00001 0.154 Antithrombin III  < 0.00001 0.202 Antithrombin III  < 0.00001 0.140 D.dimer 0.06 0.151
Fibrinogen gamma chain 0.00004 0.101 Heparin cofactor.2 0.00002 0.116 Heparin cofactor 2 0.0007 0.070 Fibrinogen gamma chain 0.07 0.179
Vitamin.K dependent protein S 0.0007 0.070 Fibrinogen gamma chain 0.00003 0.111 P.selectin 0.001 0.066 Fibrinogen 0.07 0.089
D.dimer 0.0008 0.068 D.dimer 0.00012 0.094 Fibronectin 0.009 0.042 Plasma kallikrein 0.09 0.051
Fibronectin 0.0008 0.068 P.selectin 0.0012 0.067 Vitamin.K dependent protein.S 0.015 0.037 Fibronectin Fragment.4 0.12 0.064
Prothrombin 0.007 0.044 Fibronectin 0.0014 0.066 Alpha.2 antiplasmin 0.02 0.032 Vitamin.K dependent protein.S 0.14 0.089
Heparin cofactor.2 0.009 0.042 Fibronectin Fragment.3 0.006 0.050 Prothrombin 0.05 0.024 von Willebrand factor 0.14 0.035
Fibrinogen 0.013 0.038 Fibronectin Fragment.4 0.007 0.047 Fibronectin Fragment.3 0.09 0.018 Coagulation factor.Xa 0.19 0.030
Angiostatin 0.014 0.037 Vitamin K dependent protein.S 0.02 0.037 Plasma kallikrein 0.18 0.011 Antithrombin.III 0.19 0.264
Fibronectin Fragment.3 0.03 0.031 Alpha.2 antiplasmin 0.02 0.036 Tissue Factor 0.20 0.010 Fibronectin 0.24 0.094
P.selectin 0.04 0.026 Fibrinogen 0.02 0.035 Fibrinogen gamma chain 0.24 0.009 Fibronectin Fragment.3 0.31 0.060
Alpha.2 antiplasmin 0.16 0.012 von Willebrand factor 0.12 0.016 Fibronectin Fragment.4 0.32 0.006 Tissue Factor 0.40 0.030
Fibronectin Fragment.4 0.18 0.011 Plasma kallikrein 0.18 0.012 D.dimer 0.43 0.004 Angiostatin 0.41 0.056
Tissue.Factor 0.19 0.011 Prothrombin 0.19 0.011 Angiostatin 0.50 0.003 Prothrombin 0.42 0.048
von.Willebrand factor 0.26 0.008 Coagulation factor.Xa 0.22 0.010 Coagulation Factor.XI 0.81 0.000 Alpha.2 antiplasmin 0.42 0.052
Coagulation factor Xa 0.49 0.003 Tissue.Factor 0.71 0.001 Coagulation factor.Xa 0.83 0.000 Heparin cofactor 2 0.58 0.133
Coagulation Factor.XI 0.66 0.001 Coagulation Factor.XI 0.73 0.001 von Willebrand factor 0.87 0.000 Coagulation Factor.XI 0.70 0.005
Plasma kallikrein 0.97 0.000 Angiostatin 0.74 0.001 Fibrinogen 0.93 0.000 P.selectin 0.71 0.096

Bolded numbers indicate significant differences between PCOS and control groups, at the p < 0.05 level.